Editor in Chief

Dr. Rael joined the Sean N. Parker Center for Allergy Research and the Division of Allergy, Immunology and Rheumatology at Stanford in April, 2015 after previously being on faculty at Penn State in the Division of Pulmonary, Allergy and Critical Care Medicine since 2010. He graduated from Boston University School of Medicine, completed internship at UCLA, medicine residency at Lahey Clinic, and…

Name : Efren Rael
University : Stanford University, Sean N. Parker Center for Allergy Research

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    Human Chitotriosidase in Lung and Liver Fibrosis

    Chitotriosidase may promote tissue repair responses associated with injury produced by adaptive Th2 responses in liver and pulmonary fibrosis associated with sarcoidosis. This enzyme is a useful biomarker and a potential therapeutic target in different inflammatory and fibrotic lung diseases. Its role has not been documented for all interstitial lung…

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    Spontaneous Pneumothorax during Lifting of Heavy Object: A Case Report

    Primary Spontaneous Pneumothorax (PSP) is the accumulation of air into the pleural space without any obvious history of trauma or underlying lung disease and/or radiologically evident lung lesion. Rupture of subpleural bullae or blebs are believed to be the cause of PSP. It is often seen in smoker young male. We present a case of PSP without any known…

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    Microbial Cultures of the Respiratory Tract in Familial Dysautonomia Lung Disease

    Familial Dysautonomia (FD), also known as Riley-Day Syndrome, and Hereditary Sensory and Autonomic Neuropathy type III (HSAN III), is an autosomal recessive disease mostly affecting people of Ashkenazi Jewish descent. Patients with FD have abnormal development of autonomic and sensory nervous system, resulting in malfunction of most body systems, such…

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PubMed Indexed Articles

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    Homeodomain Transcription Factor Msx-2 Regulates Uterine Progenitor Cell Response to Diethylstilbestrol

    The fate of mouse uterine epithelial progenitor cells is determined between postnatal days 5 to 7. Around this critical time window, exposure to an endocrine disruptor, diethylstilbestrol (DES), can profoundly alter uterine cytodifferentiation. We have shown previously that a homeo domain transcription factor MSX-2 plays an important role in DES-responsiveness…

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    Brain Uptake of Neurotherapeutics after Intranasal Delivery in Mice

    There is a growing global prevalence of neurodegenerative diseases such as Alzheimer’s disease and dementia. Current treatment for neurodegenerative diseases is limited due to the blood brain barrier’s ability to restrict the entry of therapeutics to the brain. In that context, direct delivery of drugs from nose to brain has gained emerging interest…

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    Current Studies of Immunotherapy on Glioblastoma

    Glioblastoma is a form of brain tumor with a very high morbidity and mortality. Despite decades of research, the best treatments currently in clinical practice only extend survival by a number of months. A promising alternative to conventional treatment for glioblastomas is immunotherapy. Although proposed over a century ago, the field of cancer immunotherapy…

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