All Special Issues
Bioinformatics Tools in Next Generation Sequencing Analysis
Dr. Shanrong Zhao,
Dr. Shanrong Zhao is Director at Computational Biology and Bioinformatics Pfizer Worldwide Research & Development, Pfizer, Cambridge. He has More than 18 years of experience in bioinformatics, statistics, genetics and large-scale data analysis, have demonstrated track of records in scientific initiative, creativity, innovation, leadership, and collaboration. A pioneer in next generation sequencing, big data analysis and cloud computing. A proven innovator with four patents, ten invited talks at international meetings, over 22 peer-reviewed publications, and a receipt of Johnson & Johnson Leadership and Innovative Awards, and Pfizer’s W.E. Upjohn Prizes Award.
About the Special Issue
Next-Generation Sequencing (NGS) has become the method of choice for molecular genetics analyses. To date, these high-throughput sequencing technologies have been comprehensively applied in a variety of ways, such as whole genome sequencing, target sequencing, gene expression profiling, chromatin immunoprecipitation sequencing, and small RNA sequencing, to accelerate biological and biomedical research. Although the time and cost for generating RNA-seq data are decreasing, the analysis of massive amounts of NGS data still remains challenging.
Numerous software packages designed to analyze massive amounts of NGS data are now publicly available. However, to select appropriate software packages can be difficult since so many similar tools are available, and the right choice often requires both an in-depth understanding of the algorithms and sufficient hands-on experience. On the other hand, not all researchers have access to a bioinformatics core or dedicated bioinformatician, and they quite often have to make the choice on their own. To help those researchers to choose appropriate tools to analyser their NGS dataset, JBCS intends to publish a special issue entitled “Bioinformatic tools in next generation sequencing analysis”.
We sincerely invite bioinformatics experts in the field of NGS data analysis to contribute review papers to cover bioinformatics in the following categories. For similar tools, please compare them head-to-head to help researchers to make informed choice.
- DNA-Seq, including algorithms for alignment, de novo assembly, and SNP calling.
- RNA-seq, including raw read QC, mapping, gene and isoform quantification, differential analysis and normalization, alternative splicing and gene fusion
- ChIP-seq to cover peak callers
- NGS dedicated visualization tools, integrated pipelines and cloud computing
The special issue is scheduled to come out in March 2017. All initial manuscripts should be submitted by late November, and the revised versions by January.
Novel Diagnosis Methods to Detect Infections Diseases
Dr. Paulo RZ Antas,
Dr. Antas has been working in a group that develops research in the field of immune response of human infections and vaccinations, especially for mucosal immunology area. Most of his scientific time, currently dedicated to study several aspects of the immune response in Tuberculosis, such as the involvement of inflammatory cytokines, and the T cells on the immune response to mycobacterium as a whole. Part of his work has also focused on identifying an immunologic predisposition to extra pulmonary tuberculosis. Thus, during his PhD degree and post-doc fellowship in Nashville (TN), he spent working in projects related to cytokine detection in patients with cured tuberculosis, studying immune responses among persons with prior extra pulmonary tuberculosis, and compared them to those responses among persons with either pulmonary or latent infection. Therefore, accumulated data have shown defects in resting cytokine production, and also have noted lower CD4 counts in HIV-seronegative patients. Primarily, these results provide evidence of defects in innate immune responses and he is raising the hypothesis of possible genetic predisposition to these immunologic defects.
About the Special Issue
The purpose of this special issue is to highlight the major findings on candidate biomarkers that intent to replace or give support to classical methods in order to accelerate the case findings, mainly in poor, low-resource settings where novel methods are desirable to improve life quality.
Metabolic Control of Diabetes
Dr. Ahmed Bakillah,
SUNY Downstate Medical Center
Dr. Ahmed Bakillah is a visiting Research Assistant Professor at Suny Downstate Medical Center, Brooklyn, NY-USA. He also currently serves as the Managing Editor of Nutrition and Metabolism Journal, BioMed Central Ltd, London-United Kingdom. He received his Ph.D. in Biochemistry from Rene Descartes Paris University in 1994. From 2000 to 2008 he worked at Pharmaceutical Companies (Novo Nordisk & GSK) as Principal Investigator. His primary research interests focus on cardiovascular metabolic diseases and lipid and lipoprotein metabolism. He has published numerous highly cited journal publications, conference articles and book chapters in the CVD and lipids field, and has received several awards and grants from various funding agencies.
About the Special Issue
Tackling diabetes is one of the major health challenges of our time. Approximately, 347 million people worldwide have diabetes; among them almost half a million children are under the age of 14. Approximately 50% of diabetics show diabetes vascular complications by the time they are diagnosed. Ongoing research is now focusing on newer alternative therapeutic agents that have potential to affect primary mechanisms contributing to the pathogenesis of vascular diabetic complications. The purpose of this special issue is to publish high-quality research papers as well as review articles addressing advances and current therapies allowing better glycemic control while minimizing the risk of metabolic and cardiovascular diseases that are associated with the progression and development of diabetes.
Potential topics include, but are not limited to:
- Metabolic dysfunction and glycemic control in diabetes.
- Update on current therapies in the pharmacological management of diabetes.
- New options for insulin analogues delivery and the problematic of hypoglycemia and weight gain.
- Gut microbiota, immunity and inflammation in diabetes.
- Epigenetics and cardiovascular disease in diabetes.
- Oxidative stress genes, antioxidants and coronary artery disease in diabetes.
- Diabetic dyslipidemia and lipid and lipoprotein metabolism: Impact of lipases
- Molecular mechanisms of metabolic dysfunction and physiopathology of vascular complications of diabetes.
- Managing diabetes in patients with chronic kidney disease.
- New insights into diabetes cell therapy.
Special Issue about Parapharyngeal Space Tumors
Dr. Afshin Teymoortash,
Philipps University, Germany
Dr. Afshin Teymoortash received his doctorate in the Department of Medicine at University of Kiel. He is Specialist in ear, nose &throat medicine and facial plastic surgery. His research areas include Head and neck oncology, plastic reconstructive surgery of the head and neck, salivary gland diseases. He is Co-Chairman of the Department of Otorhinolaryngology, Head and Neck Surgery at the Philipp University, Marburg, Germany.
About the Special Issue
The parapharyngeal space is a deep and complex anatomical space in the shapes of an inverted pyramid. Parapharyngeal space tumors are infrequent but important tumors of the head and neck region with histological diversitypresent difficult diagnostic and management challenges.
The management of these usually asymptomatic masses is diagnosis-dependent and should be individualized.Adequate evaluation and management of parapharyngeal space tumors requires beside surgical expertise in head and neck region radiological and pathological skills.
Treatment of choice in most parapharyngeal tumors is the complete surgical excision. The most frequent surgical approaches for resection of these tumors are transcervical, transparotid, and transpharyngeal via mandibulotomy. Improvements in imaging and surgical technologies have sparked renewed interest in minimaly invasive transoral approaches with TORS (transoral robotic surgery) for treatment of selected parapharyngeal tumors.
In the planned special issue all different aspects of parapharyngeal space tumors like anatomical aspects, radiological diagnostic, different pathological aspects, selection of surgical approaches, and radiotherapy should be presented.
Veterinary Alternative Medicine
Dr. Eman Ahmed,
Suez Canal University, Egypt
Eman Ahmed has received her joint PhD (Japan / Egypt) from Tokyo University of Agriculture and Technology and Suez Canal University. She is expertise in Pharmacology, Drug Toxicology, Endocrinology, Reproductive Physiology, Drug research and development, Biology and life sciences. Currently she is working as a lecturer of pharmacology and Faculty of Veterinary Medicine at Suez Canal University, Egypt.
Dr. Alper Kocyigit
Cumhuriyet University, Turkey
Dr. Alper Kocyigit received his PhD from Graduate School of Health Sciences, Ondokuz Mayis University, turkey. He joined Cumhuriyet University, Faculty of Veterinary Medicine as the teaching staff. In this role he is responsible for lectures and academic research. Embryology, artificial insemination, reproductive biotechnologies, transfer of embryos, andrology, and cryopreservation of gametes are some of these lectures. His areas of expertise are reproductive biotechnologies and cryopreservation. Kocyigit has a 10 year of veterinary medicine experience and still continues his research in this area.
About the Special Issue
JVAH is an international journal that seeks to understand the sources and to encourage rigorous research in veterinary medicine including alternative medicine and integrative medicine, yet ancient world of complementary and alternative medicine.
The journal seeks to apply scientific rigor to the study of complementary and alternative medicine modalities, particularly traditional healing systems “Ayurvedic Medicine”. Veterinary Alternative and natural Medicine emphasizes health outcome while documenting biological mechanisms of action. The journal is devoted to the advancement of science in the field of basic research, clinical studies, methodology or scientific theory in diverse areas of alternative medicine and biomedicine.