Journal of Bioinformatics, Computational and Systems Biology

Editor in Chief

Dr. Otu is Professor of Electrical and Computer Engineering at the University of Nebraska-Lincoln. Dr. Otu’s research interests are macromolecular sequence analysis, microarrays, biomarker discovery, genetic variations and systems biology, analyzing high throughput biological data within the context of networks. Dr. Otu has published over 50 journal articles and 30 peer-reviewed conference…

Name : Hasan H. Otu
University : University of Nebraska-Lincoln

Indexing and Listing



Recent Articles

PubMed Indexed Articles

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    Homeodomain Transcription Factor Msx-2 Regulates Uterine Progenitor Cell Response to Diethylstilbestrol

    The fate of mouse uterine epithelial progenitor cells is determined between postnatal days 5 to 7. Around this critical time window, exposure to an endocrine disruptor, diethylstilbestrol (DES), can profoundly alter uterine cytodifferentiation. We have shown previously that a homeo domain transcription factor MSX-2 plays an important role in DES-responsiveness…

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    Brain Uptake of Neurotherapeutics after Intranasal Delivery in Mice

    There is a growing global prevalence of neurodegenerative diseases such as Alzheimer’s disease and dementia. Current treatment for neurodegenerative diseases is limited due to the blood brain barrier’s ability to restrict the entry of therapeutics to the brain. In that context, direct delivery of drugs from nose to brain has gained emerging interest…

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    Current Studies of Immunotherapy on Glioblastoma

    Glioblastoma is a form of brain tumor with a very high morbidity and mortality. Despite decades of research, the best treatments currently in clinical practice only extend survival by a number of months. A promising alternative to conventional treatment for glioblastomas is immunotherapy. Although proposed over a century ago, the field of cancer immunotherapy…

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