Editor in Chief

Catherine M. Roe PhD. Her major research interests are in the use of biomarkers for detection and prediction of preclinical and symptomatic Alzheimer's disease (AD), in individual differences in AD manifestation, and in associations between AD biomarkers and "non-cognitive" outcomes including driving.

Name : Dr. Catherine M. Roe
University : Washington University

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Recent Articles

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    Sphenoid Sinus Mucocele with Bilateral Blindness

    Sphenoid sinus mucocele is a rare condition. Blindness is one of the complications described. It could be unilateral or bilateral. Late presentation is a major challenge as it leads to a poor outcome in the recovery of vision.

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    Guillain-Barre Syndrome Following PCV vaccine

    Guillain-Barre syndrome (GBS) is a rapid-onset muscle weakness caused by the immune system attacking the peripheral nervous system. Although the causes still remain elusive, many studies in the past have linked GBS to vaccinations, such as influenza, but pneumococcal vaccine remains to be studied. This case report highlights a woman who developed severe…

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    Colpocephaly in Chudley-McCullough Syndrome

    Chudley-McCullough syndrome is a rare autosomal recessive disorder characterized by congenital bilateral sensorineural hearing loss, partial corpus callosum agenesis, colpocephaly with a right-sided tendency and other brain abnormalities, such as an arachnoid cyst.

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PubMed Indexed Articles

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    Homeodomain Transcription Factor Msx-2 Regulates Uterine Progenitor Cell Response to Diethylstilbestrol

    The fate of mouse uterine epithelial progenitor cells is determined between postnatal days 5 to 7. Around this critical time window, exposure to an endocrine disruptor, diethylstilbestrol (DES), can profoundly alter uterine cytodifferentiation. We have shown previously that a homeo domain transcription factor MSX-2 plays an important role in DES-responsiveness…

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    Brain Uptake of Neurotherapeutics after Intranasal Delivery in Mice

    There is a growing global prevalence of neurodegenerative diseases such as Alzheimer’s disease and dementia. Current treatment for neurodegenerative diseases is limited due to the blood brain barrier’s ability to restrict the entry of therapeutics to the brain. In that context, direct delivery of drugs from nose to brain has gained emerging interest…

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    Current Studies of Immunotherapy on Glioblastoma

    Glioblastoma is a form of brain tumor with a very high morbidity and mortality. Despite decades of research, the best treatments currently in clinical practice only extend survival by a number of months. A promising alternative to conventional treatment for glioblastomas is immunotherapy. Although proposed over a century ago, the field of cancer immunotherapy…

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