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  • Case report - Medical Published: Sep 10, 2015

    A Case of Effective Correction of SIADH with Low Dose Tolvaptan: No Trade of for an Economic Benefit

    Hyponatremia is a common electrolyte abnormality in the hospital setting and can cause significant morbidity and mortality. Syndrome of anti diuretic hormone (SIADH) secretion can pose management difficulties particularly if the etiology is not easily reversed. Fluid restriction as a treatment option is complicated in the acutely unwell patient, and…

    -Ruth Casey, Michelle Canavan, Michael Dennedy, Paula O Shea, Sylvia Blaskove and Marcia Bell

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  • Editorial - Medical Published: Sep 16, 2015

    Endocrine Disruptors and their Harmful Health Implications: Between Old Thoughts and New Findings

    Many environmental chemicals, such as pesticides, have been experimentally demonstrated that they adversely affect the endocrine processes, known as endocrine disruptors (EDs). Endocrine disrupting chemicals are endocrine-modifying substances that have “weak intrinsic hormonal or anti-hormonal activity” and affect the balance of normal hormonal functions [1,2]. Several studies regarding exposure to…

    -Eman Ahmed, Mohamed M. Abdel-Daim

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  • Editorial - Pharmacy Published: Sep 09, 2015

    Will Diseases Become More Predictable, Treatable and Curable?

    Unfortunately, there are rare or no effective treatments for quite a few diseases, such as cancer, AD and PD. Understanding the pathology and etiology is the first step, with great achievements having taken place over the last few decades. Next, these research achievements must be translated into effective therapeutics or…

    -Pan Chen

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  • Editorial - Lifesciences Published: Sep 11, 2015

    Small "Crossovers" of Metabolic Processes but Potentially Great Factors of Health or Disease

    In biological systems, cellular metabolism is dependent on energy production. The main route of ATP synthesis in all eukaryotes is mitochondrial oxidative phosphorylation. Reactive oxygen species production occurs as a result of electron transfer reactions. Although mitochondria are responsible for the continuous production of reactive oxygen species, they are not…

    -Janka Vaskova

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  • Editorial - Medical Published: Sep 10, 2015

    Tinnitus: A Challenging Complaint for the Physician

    Tinnitus is a common but very heterogeneous symptom. It is defined as the perception of a sound by an individual in the absence of an external source or stimuli from the external environment. There are various causes for tinnitus, which complicates its understanding and study. There is also a great…

    -Fernando L.Fernandes, Alexandre C. Guimaraes, Reinaldo J. Gusmao

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