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Latest Articles

  • Review article - Medical Published: Jun 16, 2017

    Management of the Axilla in Breast Cancer - Routine Practice, Controversies and Outlook

    Surgery is the cornerstone of breast cancer treatment. History of breast cancer is correlated with the history of its surgical management. Surgical practices have evolved from the William Stewart Halsted time. Initially, loco regional treatments were very mutilating. They have been refined since the systematization of sentinel node biopsy in…

    -Sidy Ka, Pape M. Gaye, Serigne M. Badiane, Doudou Diouf, Mamour Gueye, and Ahmadou Dem

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  • Review article - Lifesciences Published: Jun 20, 2017

    Induced Pluripotent Stem Cells: An Innovative Patient-Specific Neurodegenerative Disease Modeling

    Recent Progress in pluripotent stem cell biology has nourished the hope to use for brain repair stem cell based therapy. Cell reprogramming diseases models seems particularly hopeful in the field of human neurological disorders including Alzheimer’s disease, Parkinson’s disease, and amyotrophic lateral sclerosis, for which animal models could be not…

    -Gabriele Bonaventura1*, Maria L. Barcellona2, Iemmolo Rosario1, and Sebastiano Cavallaro1

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  • Research article - Medical Published: Jun 19, 2017

    Hypoxia-Inducible Factor in Cord Blood of Term and Preterm Newborns

    The Hypoxia Inducible Factor-1 (HIF-1) is a transcription pivotal molecule regulating cellular homeostasis in response to hypoxia. It has been shown to up regulate various downstream genes – e.g. Erythropoietin (EPO) and Vascular Endothelial Growth Factor (VEGF) – and has been implicated in the pathogenesis of several diseases involving tissue…

    -Patrizia Zaramella, Valentina Vanzo, Romilda Cardin, Marika Piciocchi, Alessandra Zambon, Francesca

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  • Case report - Medical Published: Jun 03, 2017

    Apparent Improvement of Airway Injury after Gene-Potentiating Therapy in Cystic Fibrosis

    Patients with cystic fibrosis (CF) and suitable genotypes are now able to access gene-potentiating therapy that improves lung function, weight gain, and prolongs the time between pulmonary exacerbations. We report the case of a 74 year old woman who had CF with a R117H gating mutation. Lung function had declined…

    -Hayley Barnes, Trevor Williams, Dominic Keating and John Wilson

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  • Research article - Lifesciences Published: Jun 20, 2017

    Antimicrobial Potential in Biogenic Silver Nanoparticles Synthesized from Plectranthus zeylanicus

    Out of all metals, silver has been widely recognized for its antimicrobial activity over centuries of years. In more recent times, silver was found to be even more effective in antimicrobial activity when it was at nanoscale. A novel protocol was developed for green synthesis of silver nanoparticles and their…

    -Sudhara G. De Soyz, W.M.D Gaya Bandara Wijayaratne2, Mayuri Napagoda and Sanjeeva Witharana

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